8.05740

2-Mercaptoethanol

for synthesis

• 别名: 2-巯基乙醇, β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇
• 线性分子式: HSCH₂CH₂OH
• CAS号: 60-24-2
• 分子量: 78.13
• Beilstein: 773648
• MDL编号: MFCD00004890
• UNSPSC代码: 12352104
• EC索引号: 200-464-6
• NACRES: NA.22

属性

• 蒸汽密度: 2.69 (vs air)
• 质量水平: 200
• 蒸汽压: 1 mmHg ( 20 °C)
• 方案: ≥99% (GC)
• 表单: liquid
• 自燃温度: 295 °C
• 效能: 98-162 mg/kg LD₅₀, oral (Rat); 112-224 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 18 %
• 反应适用性: reagent type: reductant
• 浓度: 14.3 M (pure liquid)
• 折射率: n20/D 1.500 (lit.)
• pH值（酸碱度）: 4.5-6 (20 °C, 500 g/L in H₂O)
• 沸点: 157 °C (lit.)
• mp: <-50 °C
• 转变温度: flash point 70.5 °C
• 密度: 1.114 g/mL at 25 °C (lit.)
• 储存温度: 2-30°C
• SMILES字符串: OCCS
• InChI: 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
• InChI key: DGVVWUTYPXICAM-UHFFFAOYSA-N

说明

应用

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

安全信息

• 象形图: GHS05,GHS06,GHS08,GHS09
• 警示用语：: Danger
• 危险声明: H301 + H331 - H310 - H315 - H317 - H318 - H361d - H373 - H410
• 预防措施声明: P273 - P280 - P301 + P310 - P302 + P352 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• 危险分类: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral
• 储存分类代码: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 闪点(°F): 165.2 °F - closed cup
• 闪点(°C): 74 °C - closed cup