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8.00683

Sigma-Aldrich

琥珀酸酐

for synthesis

别名:

琥珀酸酐

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About This Item

经验公式(希尔记法):
C4H4O3
CAS号:
分子量:
100.07
MDL编号:
UNSPSC代码:
12352115
EC索引号:
203-570-0
NACRES:
NA.22
价格与库存信息目前不能提供

蒸汽压

1.3 hPa ( 92 °C)

质量水平

表单

crystals

自燃温度

480 °C

效能

1510 mg/kg LD50, oral (Rat)

pH值(酸碱度)

2.7 (10 g/L in H2O)

沸点

261 °C/1013 hPa

mp

116-120 °C

转变温度

flash point 157 °C

溶解性

62.9 g/L (Hydrolysis)

密度

1.23 g/cm3 at 20 °C

堆积密度

550‑600 kg/m3

储存温度

2-30°C

SMILES字符串

O1C(=O)CCC1=O

InChI

1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2

InChI key

RINCXYDBBGOEEQ-UHFFFAOYSA-N

应用

  • 增强抗菌纤维:琥珀酸酐用于偶联壳聚糖与麻兰和大麻纤维以生产抗菌纤维,显著提高它们在医药卫生产品中的用处(Barker et al., 2024)。
  • 抗肿瘤二萜类:琥珀酸酐是拟红紫珠合成的新克罗烷二萜的一部分,这种二萜具有抗肿瘤增殖活性(Pan et al., 2024)。
  • 纳米凝胶递送系统:用于开发纳米凝胶递送系统用于运送阳离子肽药物以改善药物递送,表明它在药物递送系统中的多功能作用(Mørck Nielsen et al., 2024)。

分析说明

含量测定(吗啉法): ≥ 98.0%(m)
鉴别(IR):符合
熔程(下限值): ≥ 116 °C
熔程(上限值): ≤ 120 °C

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 1

闪点(°F)

314.6 °F

闪点(°C)

157 °C


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Ananthakrishnan Soundaram Jeevarathinam et al.
Angewandte Chemie (International ed. in English) (2019-12-17)
We report a new approach to monitor drug release from nanocarriers via a paclitaxel-methylene blue conjugate (PTX-MB) with redox activity. This construct is in a photoacoustically silent reduced state inside poly(lactic-co-glycolic acid) (PLGA) nanoparticles (PTX-MB@PLGA NPs). During release, PTX-MB is

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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