476475

PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated

The PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 别名: PKC Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myr-N-RKRTLRRL-OH, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated, Myristoylated EGF-R Fragment (651-658), Protein Kinase C Inhibitor, Myr-N-RKRTLRRL-OH, Protein Kinase C Inhibitor, EGF-R Fragment 651-658, Myristoylated
• 经验公式（希尔记法）: C₆₀H₁₁₇N₂₁O₁₁
• 分子量: 1308.71
• 分類程式碼代碼: 12352202
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥97% (HPLC)
• 形狀: lyophilized solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated
• 溶解度: water: 5 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC₅₀ = 5 µM) in intact cells.

Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-ErbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor of protein kinase C (IC₅₀ = 5 µM).

生化／生理作用

Cell permeable: yes

Primary Target
PKC

Product does not compete with ATP.

Reversible: yes

Target IC₅₀: 5 µM against protein kinase C

包裝

Yes

警告

Toxicity: Standard Handling (A)

序列

Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

外觀

Supplied as a trifluoroacetate salt.

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

其他說明

Ward, N.E., and O’Brian, C.A. 1993. Biochemistry32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable