444221

MMP-1/MMP-9 Substrate, Fluorogenic

An excellent quenched fluorescence substrate for MMP-1 and MMP-9.

• 别名: MMP-1/MMP-9 Substrate, Fluorogenic
• 经验公式（希尔记法）: C₄₉H₆₈N₁₄O₁₂S
• 分子量: 1077.22
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: yellow
• 溶解度: 50% acetic acid: 10 mg/mL
• 螢光: λ_ex ~365 nm; λ_em ~450 nm
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

An excellent quenched fluorescence substrate for MMP-1 and MMP-9 (excitation maximum: 365 nm; emission maximum: 450 nm). Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining K_i values. Excitation max: ~365 nm; emission max: ~450 nm.

An excellent quenched fluorescence substrate for MMP-1 and MMP-9. Both enzymes cleave this substrate between Gly and Cys(Me), liberating a fluorescent cleavage product. Suitable for inhibitor screening and determining K_i values.

生化／生理作用

Cell permeable: no

Primary Target
MMP-1, MMP-9

Product does not compete with ATP.

Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

序列

{DNP-Pro-Cha-Gly-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abz = 2-aminobenzoyl (anthraniloyl)]

其他說明

Bickett, D.M., et al. 1993. Anal. Biochem. 212, 58.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable