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Merck

1.16881

Millipore

Fractogel EMD TMAE (M)

别名:

Fractogel® EMD TMAE (M)

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About This Item

分類程式碼代碼:
41115711
价格与库存信息目前不能提供

ligand

(Trimethylammoniumethyl)

品質等級

描述

strong anion exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)

無菌

sterile (Caustic Stable)

產品線

Fractogel®

形狀

resin

參數

240 cm/hr flow rate
8 bar max. pressure

基質活性組

methacrylate

平均粒徑

40-90 μm

容量

100 mg binding capacity (BSA/mg of resin)

轉變溫度

flash point 35 °C (calculated)

密度

1.430 g/cm3 at 20 °C

體積密度

1000 kg/m3

應用

gene therapy
mAb
recombinant protein

分離技術

anion exchange
strong anion exchange

儲存溫度

no temp limit

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一般說明

Strong anion exchange Fractogel® resin featuring the tentacle technology with a trimethylammoniumethyl functional group, for purification of acidic and neutral proteins and peptides from multiple sources, DNA and virus removal, plasmid isolation, vaccine purification, and more

特點和優勢

Fractogel® EMD TMAE (M) enables:

  • High protein loading conditions resulting in good selectivity and resolution with the tentacle technology
  • Excellent binding to large viruses at increased loading
  • Homogenous binding with high selectivity and purity
  • Reduce operating costs and resin replacement with enduring durability - allowing for multiple cycles of column regeneration and sanitization
  • Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution

包裝

  • 1.16881.0100: Fractogel® EMD TMAE (M) Resin 100ml
  • 1.16881.0010: Fractogel® EMD TMAE (M) Resin 10ml
  • 1.16881.0500: Fractogel® EMD TMAE (M) Resin 500ml
  • 1.16881.0050: Fractogel® EMD TMAE (M) Resin 50ml
Plastic bottle

分析報告

Appearance: Milky turbid suspension, free from impurities (foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.03 %
Cerium: ≤ 1 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (bovine serum albumin): 80 - 120 mg/ml
Functional test (b:a): ≤ 0.25
Functional test: Separation of conalbumin and human serum albumin

法律資訊

FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany

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象形圖

Flame

訊號詞

Warning

危險聲明

危險分類

Flam. Liq. 3

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

95.0 °F

閃點(°C)

35 °C


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A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understanding, simulates bottlenecks, and helps to optimize production efficiency.

A custom-designed cost model is used to explore the economics of vaccine manufacturing across several different modalities including mRNA. The model enables greater process understanding, simulates bottlenecks, and helps to optimize production efficiency.

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