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Merck
所有图片(1)

主要文件

07-535

Sigma-Aldrich

抗MKP1抗体

Upstate®, from rabbit

别名:

Anti-CL100, Anti-HVH1, Anti-MKP-1, Anti-MKP1, Anti-PTPN10

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human, mouse

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... FARSB(10056)

特異性

识别MKP1。

免疫原

对应于人MAP激酶磷酸酶1(MKP1)氨基酸87-101(DERSAALDGAKRDGT-C)的肽

應用

抗MKP1抗体经过验证可用在WB中检测MKP1。
研究子类别
激酶 & 磷酸酶
研究类别
信号传导

品質

已通过免疫印迹法对3T3/A31细胞的RIPA裂解液进行了常规评估

標靶描述

42 kDa

外觀

形式:纯化
蛋白A纯化
蛋白A纯化的免疫球蛋白,溶于30%甘油,0.07M Tris-甘氨酸(pH 7.4)、0.105 M NaCl,0.035%叠氮化钠作为防腐剂的溶液中。

儲存和穩定性

自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。

分析報告

对照
阳性抗原对照:目录号12-305,3T3/A31裂解液。加入2.5 μL 2-巯基乙醇/100 μL裂解液,煮沸5分钟以还原样本。在微凝胶每个泳道上样20 μg经还原的裂解液。

其他說明

浓度:请参考批次特异性浓缩物的分析证书。

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析证书(COA)

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Akira Imasato et al.
The Journal of biological chemistry, 277(49), 47444-47450 (2002-10-03)
Despite the importance of glucocorticoids in suppressing immune and inflammatory responses, their role in enhancing host immune and defense response against invading bacteria is poorly understood. We have demonstrated recently that glucocorticoids synergistically enhance nontypeable Haemophilus influenzae (NTHi)-induced expression of
Shen-Hsi Yang et al.
PLoS genetics, 8(12), e1003112-e1003112 (2012-12-29)
Embryonic stem cells and induced pluripotent stem cells represent potentially important therapeutic agents in regenerative medicine. Complex interlinked transcriptional and signaling networks control the fate of these cells towards maintenance of pluripotency or differentiation. In this study we have focused
C F Zheng et al.
The Journal of biological chemistry, 268(22), 16116-16119 (1993-08-05)
The activation of extracellular signal-regulated kinase (ERK) or mitogen-activated protein kinase (MAPK) by a dual specific kinase, MEK (MAPK or ERK kinase), is a critical event in the mitogenic signal transduction pathway. However, little is known about the mechanism of
Marina Lasa et al.
Molecular and cellular biology, 22(22), 7802-7811 (2002-10-23)
The stress-activated protein kinase p38 stabilizes a number of mRNAs encoding inflammatory mediators, such as cyclooxygenase 2 (Cox-2). In HeLa cells the anti-inflammatory glucocorticoid dexamethasone destabilizes Cox-2 mRNA by inhibiting p38 function. Here we demonstrate that this effect is phosphatase
Epinephrine and AICAR-induced PGC-1? mRNA expression is intact in skeletal muscle from rats fed a high-fat diet.
Frier, BC; Wan, Z; Williams, DB; Stefanson, AL; Wright, DC
American Journal of Physiology. Cell Physiology null

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