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Merck
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主要文件

07-357

Sigma-Aldrich

Anti-phospho-eNOS/NOS III (Ser114) Antibody

Upstate®, from rabbit

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

human, bovine

制造商/商品名称

Upstate®

技术

western blot: suitable

同位素/亚型

IgG

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

phosphorylation (pSer114)

基因信息

bovine ... Nos3(287024)
human ... NOS3(4846)

一般描述

Note: ADMA (Catalog #19-169) and NMMA (Catalog #19-170) are inhibitors of NOS

特异性

eNOS/NOS III phosphorylated on serine 114

免疫原

Synthetic peptide corresponding to amino acids 106-118 of human eNOS/NOS III (Ser114) (PRKLQGRPpSPGPP-C) with a C-terminal cysteine added for conjugation to KLH. The immunizing sequence shares 12/13 amino acids with pig and bovine eNOS/NOS III.

应用

Detect phospho-eNOS/NOS III (Ser114) using this Anti-phospho-eNOS/NOS III (Ser114) Antibody validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

质量

routinely evaluated by immunoblot in fetal bovine heart endothelial cell lysate

目标描述

132 kDa

外形

Immunoaffinity Chromatography
0.2 M Tris-glycine, pH 7.4, 0.15 M NaCl, 0.1 mM EDTA, and 0.05% sodium azide before the addition of glycerol to 30%

储存及稳定性

1 year at -20°C

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1


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Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL.
Accordi, Benedetta, et al.
Testing, 5, e13552-e13552 (2010)
Stuart A Ritchie et al.
The Biochemical journal, 426(1), 85-90 (2009-11-21)
Insulin stimulates endothelial NO (nitric oxide) synthesis via PKB (protein kinase B)/Akt-mediated phosphorylation and activation of eNOS (endothelial NO synthase) at Ser-1177. In previous studies, we have demonstrated that stimulation of eNOS phosphorylation at Ser-1177 may be required, yet is
Shiqin Xiong et al.
The Journal of clinical investigation, 130(7), 3684-3698 (2020-04-17)
Unchecked inflammation is a hallmark of inflammatory tissue injury in diseases such as acute respiratory distress syndrome (ARDS). Yet the mechanisms of inflammatory lung injury remain largely unknown. Here we showed that bacterial endotoxin lipopolysaccharide (LPS) and cecal ligation and

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