05-23-3831

BQ-123, Sodium Salt

A highly potent, selective, and competitive ETA (endothelin) receptor antagonist (K_i = 40 nM for ETA versus K_i = 2.5 µM for ETB).

• 别名: BQ-123, Sodium Salt
• 经验公式（希尔记法）: C₃₁H₄₁N₆O₇ · Na
• 分子量: 632.68
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥95% (HPLC)
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; desiccated (hygroscopic)
• 顏色: white
• 溶解度: water: 1 mg/mL
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

一般說明

A highly potent and selective ET_A (endothelin) receptor antagonist (K_i = 40 nM for ET_A versus 2.5 µM for ET_B).

A highly potent, selective, and competitive ET_A (endothelin) receptor antagonist (K_i = 40 nM for ET_A versus K_i = 2.5 μM for ET_B).

生化／生理作用

Cell permeable: no

Primary Target
ETA (endothelin) receptor antagonist

Product does not compete with ATP.

Reversible: no

Target K_i: 40 nM for ETA versus 2.5 µM for ETB

包裝

Yes

警告

Toxicity: Standard Handling (A)

序列

Cyclo(D-Asp-Pro-D-Val-Leu-D-Trp, Na)

外觀

Supplied as a sodium salt. Sold on the basis of peptide content.

其他說明

Nambi, P., et al. 1996. J. Pharmacol. Exp. Ther.277, 1567.
Bax, W.A., and Saxena, P.R. 1994. Trends Pharmacol. Sci. 15, 379.
Ihara, M., et al. 1991. Biochem. Biophys. Res. Commun. 178, 132.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable