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P63204

Sigma-Aldrich

2,3-吡啶二甲酸

99%

别名:

喹啉酸

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About This Item

经验公式（希尔记法）:
C7H5NO4
CAS号:
89-00-9
分子量:
167.12
Beilstein:
137110
EC 号:
201-874-8
MDL编号:
MFCD00006295
UNSPSC代码:
12352100
PubChem化学物质编号:
24278005
NACRES:
NA.22
价格与库存信息目前不能提供

质量水平

100

方案

99%

表单

powder

mp

188-190 °C (dec.) (lit.)

SMILES字符串

OC(=O)c1cccnc1C(O)=O

InChI

1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)

InChI key

GJAWHXHKYYXBSV-UHFFFAOYSA-N

基因信息

rat ... Gria1(50592) , Grin2a(24409)

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相关类别

应用

抑制葡萄糖合成。[1]

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H319,H335

危险分类

Eye Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCW5881
WXBD9442V
MKCR9642
MKCP0259
MKCM1590

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Dorit Cohen-Carmon et al.
Molecular neurobiology, 57(3), 1768-1777 (2019-12-14)
Huntington's disease (HD) is a neurodegenerative late-onset genetic disorder caused by CAG expansions in the coding region of the Huntingtin (HTT) gene, resulting in a poly-glutamine (polyQ) expanded HTT protein. Considerable efforts have been devoted for studying HD and other
L Garcia-Salguero et al.
Archives internationales de physiologie, de biochimie et de biophysique, 99(3), 237-242 (1991-06-01)
The in vitro and in vivo effects of several different inhibitors of carbohydrate metabolism have been studied. The in vitro addition of 5-methoxyindole-2-carboxylic acid (MICA), pent-4-enoic acid, and quinolinic acid to the perfusion medium significantly inhibited liver gluconeogenesis in 48-hour-starved
Gilles J Guillemin
The FEBS journal, 279(8), 1356-1365 (2012-01-18)
Over the last two decades, evidence for the involvement of quinolinic acid (QUIN) in neuroinflammatory diseases has been exponentially increasing. Within the brain, QUIN is produced and released by infiltrating macrophages and activated microglia, the very cells that are prominent
Valéry Combes et al.
Trends in parasitology, 28(8), 311-319 (2012-06-26)
Homeostasis implies constant operational defence mechanisms, against both external and internal threats. Infectious agents are prominent among such threats. During infection, the host elicits the release of a vast array of molecules and numerous cell-cell interactions are triggered. These pleiomorphic
Gilles J Guillemin et al.
Neuro-degenerative diseases, 2(3-4), 166-176 (2006-08-16)
The kynurenine pathway (KP) is a major route of L-tryptophan catabolism leading to production of several neurobiologically active molecules. Among them is the excitotoxin quinolinic acid (QUIN) that is known to be involved in the pathogenesis of several major inflammatory
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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