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Merck

A55004

Sigma-Aldrich

4-(2-氨乙基)-吗啉

99%

别名:

2-氨乙基吗啉

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About This Item

经验公式(希尔记法):
C6H14N2O
CAS号:
分子量:
130.19
Beilstein:
104378
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

99%

形狀

solid

折射率

n20/D 1.476 (lit.)

bp

205 °C (lit.)

密度

0.992 g/mL at 25 °C (lit.)

SMILES 字串

NCCN1CCOCC1

InChI

1S/C6H14N2O/c7-1-2-8-3-5-9-6-4-8/h1-7H2

InChI 密鑰

RWIVICVCHVMHMU-UHFFFAOYSA-N

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應用

由于4-(2-氨基乙基)吗啉可用作重要的溶酶体靶向基团,因此其已广泛用于生物医学应用中。 它的一些应用包括:
  • 在活细胞硫化氢成像过程中,用于溶酶体靶向荧光探针的合成。
  • 合成1,8-萘二甲酰亚胺缀合的Troger碱,以用作靶向脱氧核糖核酸(DNA)的荧光探针。
  • 用于分子内电荷转移-光诱导电子转移-荧光共振能量转移(ICT-PET-FRET)荧光探针的合成,其可用于监测活细胞的pH变化。
  • 它还可用作合成各种抗微生物剂的前体。

象形圖

CorrosionExclamation mark

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Skin Corr. 1B - Skin Sens. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

186.8 °F - closed cup

閃點(°C)

86 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Danford Mhule et al.
International journal of pharmaceutics, 550(1-2), 149-159 (2018-08-21)
Stimuli-responsive nano-drug delivery systems can optimize antibiotic delivery to infection sites. Identifying novel lipids for pH responsive delivery to acidic conditions of infection sites will enhance the performance of nano-drug delivery systems. The aim of the present investigation was to
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International journal of molecular sciences, 21(16) (2020-08-17)
The present study aimed to design and synthesize a new series of hybrid compounds with pyrrolidine-2,5-dione and thiophene rings in the structure as potential anticonvulsant and antinociceptive agents. For this purpose, we obtained a series of new compounds and evaluated
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Liu T, et al.
Organic Letters, 15(9), 2310-2313 (2013)
Synthesis of some new 1, 2, 4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities.
Bayrak H, et al.
European Journal of Medicinal Chemistry, 44(3), 1057-1066 (2009)
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Vooturi S K, et al.
Journal of Medicinal Chemistry, 52(16), 5020-5031 (2009)

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