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Merck

A10507

Sigma-Aldrich

丙酮肟

98%

别名:

β-异亚硝基丙烷, 2-丙酮肟, N-异丙基亚基羟胺, 丙酮肟, 二甲基酮肟

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About This Item

线性分子式:
(CH3)2C=NOH
CAS号:
分子量:
73.09
Beilstein:
1560146
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.02

方案

98%

表单

crystals

沸点

135 °C (lit.)

mp

60-63 °C (lit.)

密度

0.901 g/mL at 25 °C (lit.)

SMILES字符串

C\C(C)=N/O

InChI

1S/C3H7NO/c1-3(2)4-5/h5H,1-2H3

InChI key

PXAJQJMDEXJWFB-UHFFFAOYSA-N

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Danger

危险分类

Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Flam. Sol. 2 - Skin Sens. 1B

储存分类代码

4.1B - Flammable solid hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Stefanie Zorbas-Seifried et al.
Molecular pharmacology, 71(1), 357-365 (2006-10-20)
The presence of cis-configured exchangeable ligands has long been considered a prerequisite for antitumor activity of platinum complexes, but over the past few years, several examples violating this structure-activity relationship have been recognized. We report here on studies with the
M Rysková et al.
Folia biologica, 43(1), 19-24 (1997-01-01)
The genotoxic effects of N-nitroso-N-methylurea (MNU) and acetone oxime (ACOX) were tested in the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. We have performed the same assay on transgenic flies expressing the human gene encoding a glutathione S-transferase
C Kohl et al.
Carcinogenesis, 13(7), 1091-1094 (1992-07-01)
The hepatocarcinogenicity of acetoxime has been tentatively linked with its metabolic oxidation to the potent genotoxicant and carcinogen propane 2-nitronate (P2-N). In order to test the hypothesis that acetoxime is metabolized to P2-N, the oxime (20 mM) was incubated with
N Guo et al.
Carcinogenesis, 11(9), 1659-1662 (1990-09-01)
The hepatocarcinogens 2-nitropropane and acetoxime have previously been found to induce a specific and qualitatively identical pattern of base damage in rat liver DNA and RNA, including the induction of increased levels of 8-hydroxyguanine. Because both 2-nitropropane and acetoxime are
A A Caro et al.
Nitric oxide : biology and chemistry, 5(4), 413-424 (2001-08-04)
Ketoximes undergo a cytochrome P450-catalyzed oxidation to nitric oxide and ketones in liver microsomes. In addition, nitric oxide synthase (NOS) can catalyze the oxidative denitration of the >C=N-OH group of amidoximes. The objective of this work was to characterize the

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