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形狀
pellets
品質等級
饋電比
lactide:glycolide 50:50
分子量
PEG average Mn 2,000
PLGA average Mn 11,500
average Mn 13,500 (total)
降解時間
1-4 weeks
轉變溫度
Tm 298-303 °C
Tg 40 °C (PDLLA block)
Tg 6 °C (PEG block)
蛋白質二硫鍵異構酶
≤2.0
儲存溫度
2-8°C
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一般說明
两亲性嵌段共聚物（AmBC）由两种化学上不同的均聚物嵌段组成。嵌段之一是亲水的而另一种是疏水的。这些大分子在溶于水性介质时具有自组装的特性。PEG-PLGA是于药物递送应用的最常见可生物降解两亲嵌段共聚物之一。PEG是亲水部分而PLGA是疏水部分。
應用
用于合成用于药物差异递送和受控释放的靶向纳米颗粒。
特點和優勢
- 良好的生物相容性，低免疫原性和良好的可降解性。
- 可通过改变嵌段共聚物链段的尺寸以适合特定应用而轻松对属性进行调节。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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Micelle formation addresses low solubility in IV drug delivery, overcoming clinical limitations.
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