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表单
solid
质量水平
投料比
lactide:glycolide 50:50
分子量
PEG average Mn 5,000
PLGA Mn 7,000
average Mn 12,000 (total)
降解时间线
1-4 weeks
转变温度
Tg 24 °C
Tm 38-43 °C
PDI
<2.0
储存温度
2-8°C
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一般描述
两亲性嵌段共聚物(AmBC)由两种化学上不同的均聚物嵌段组成。嵌段之一是亲水的,另一个是疏水的。这些大分子溶于水介质时具有自组装的特性。PEG-PLGA是最常用于药物递送应用的可生物降解的两亲嵌段共聚物之一。PEG是亲水部分,PLGA是疏水部分。
应用
可用于合成靶向纳米粒子,从而用于差异递送和控释药物。
形成“隐形”聚乙二醇化微粒
特点和优势
- 良好的生物相容性、低免疫原性和良好的降解性。
- 通过改变嵌段共聚物链段的尺寸可以轻松调节其性能,以适合特定应用。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
No data available
闪点(°C)
No data available
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商品
Micelle formation addresses low solubility in IV drug delivery, overcoming clinical limitations.
Micelle formation addresses low solubility in IV drug delivery, overcoming clinical limitations.
Micelle formation addresses low solubility in IV drug delivery, overcoming clinical limitations.
Micelle formation addresses low solubility in IV drug delivery, overcoming clinical limitations.
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