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760668

Sigma-Aldrich

二苯并环辛基马来酰亚胺

for Copper-free Click Chemistry

别名:

DBCO-马来酰亚胺

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About This Item

经验公式（希尔记法）:
C25H21N3O4
分子量:
427.45
MDL编号:
MFCD22380750
UNSPSC代码:
12352111
PubChem化学物质编号:
329766887
NACRES:
NA.22

表单

solid

反应适用性

reaction type: click chemistry
reagent type: cross-linking reagent

官能团

maleimide

储存温度

−20°C

SMILES字符串

O=C(N1CCC(NCCC(N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4)=O)=O)C=CC1=O

InChI

1S/C25H21N3O4/c29-22(14-16-27-23(30)11-12-24(27)31)26-15-13-25(32)28-17-20-7-2-1-5-18(20)9-10-19-6-3-4-8-21(19)28/h1-8,11-12H,13-17H2,(H,26,29)

InChI key

NHFQNAGPXIVKND-UHFFFAOYSA-N

相关类别

应用

马来酰亚胺功能化环辛炔衍生物，用于将环辛炔基团掺入含巯基化合物或生物分子。环辛烯在促进无铜叠氮炔环加成反应中是有用的。这种二苯并环辛炔将与叠氮官能化化合物或生物分子反应，而不需要 Cu (I) 催化剂产生稳定的三唑键。

应用包括：
  • 蛋白-肽结合物
  • 抗体酶或抗体-药物偶联物
  • 蛋白或肽-寡核苷酸结合物
  • 表面改性

象形图

Environment
GHS09

警示用语：

Warning

危险声明

H400

预防措施声明

P273

危险分类

Aquatic Acute 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCW1170
MKCW5477
MKCT1472
MKCR9310
MKCR5605

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Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

无铜点击化学

无铜点击化学是点击化学的一种替代方法，可在较低的活化屏障下进行，且没有细胞毒性过渡金属催化剂。

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