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Merck

756822

Sigma-Aldrich

氧化氘

filtered, 99.8 atom % D

别名:

氘化水, 氘代水, 重水

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About This Item

经验公式(希尔记法):
D2O
CAS号:
分子量:
20.03
EC號碼:
MDL號碼:
分類程式碼代碼:
12352303
PubChem物質ID:
NACRES:
NA.12

同位素純度

99.8 atom % D

形狀

liquid

技術

HPLC: suitable
bio NMR: suitable
protein expression: suitable

bp

101.4 °C (lit.)

mp

3.8 °C (lit.)

密度

1.107 g/mL at 25 °C

SMILES 字串

[2H]O[2H]

InChI

1S/H2O/h1H2/i/hD2

InChI 密鑰

XLYOFNOQVPJJNP-ZSJDYOACSA-N

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一般說明

氧化氘(D2O)也称为重水。它是水的氘化形式, H2O 中的两个质子被氘同位素所取代。

應用

D2O 可用作以下应用中的溶剂:      
  • 高分辨率NMR(核磁共振)
  • FTIR (傅里叶变换红外)      
  • 生物核磁共振研究    
  • 极化可见光拉曼光谱研究
  • 蛋白质表达

D2O 可通过H-D交换反应制备氘标记化合物,用于制药、生物分析、生物、环境化学等领域,可使用合适的分析方法研究药物代谢机制、反应机制、生物分子结构、食品残留农药等。.

包裝

该产品可以大包装形式供货,也可按需进行包装。 如需关于价格、供货形式及包装的信息,请联系稳定同位素客户服务

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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R Schweitzer-Stenner et al.
Journal of the American Chemical Society, 123(39), 9628-9633 (2001-09-27)
We have measured the polarized visible Raman and FTIR spectra of trialanine and triglycine in D(2)O at acid, neutral, and alkaline pD. From the Raman spectra we obtained the isotropic and the anisotropic scattering. A self-consistent spectral analysis of the
Raphael Böhm et al.
Structure (London, England : 1993), 28(2), 206-214 (2019-12-22)
The voltage-dependent anion channel (VDAC) forms the primary diffusion pore of the outer mitochondrial membrane. In its apo form, VDAC adopts an open conformation with high conductance. States of lower conductance can be induced by ligand binding or the application
Lars Holm et al.
American journal of physiology. Endocrinology and metabolism, 304(8), E895-E907 (2013-02-21)
A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body
Takhar Kasumov et al.
American journal of physiology. Heart and circulatory physiology, 304(9), H1201-H1214 (2013-03-05)
Traditional proteomics provides static assessment of protein content, but not synthetic rates. Recently, proteome dynamics with heavy water ((2)H2O) was introduced, where (2)H labels amino acids that are incorporated into proteins, and the synthesis rate of individual proteins is calculated
Timon T Wyatt et al.
Carbohydrate research, 411, 49-55 (2015-05-15)
Different fungi, including the genera Neosartorya, Byssochlamys and Talaromyces, produce (asco)spores that survive pasteurization treatments and are regarded as the most stress-resistant eukaryotic cells. Here, the NMR analysis of a series of trehalose-based oligosaccharides, being compatible solutes that are accumulated

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Protein structure analysis aids in identifying disease biomarkers and drug targets crucial for therapeutic treatments.

蛋白质结构提供有价值的信息,用于推断蛋白质功能。研究蛋白质结构,对蛋白质的相互作用、表达水平和位置作图能够确定疾病的生物标志物和用于治疗的潜在药物靶点。

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