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Merck

56951

Sigma-Aldrich

N -(2-氨乙基)马来酰亚胺 三氟乙酸盐

≥98% (T), for peptide synthesis

别名:

2-马来酰亚胺乙胺 三氟乙酸盐

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About This Item

经验公式(希尔记法):
C6H8N2O2 · C2HF3O2
分子量:
254.16
MDL编号:
UNSPSC代码:
12161502
PubChem化学物质编号:
NACRES:
NA.22
价格与库存信息目前不能提供

产品名称

N -(2-氨乙基)马来酰亚胺 三氟乙酸盐, ≥95% (HPLC), ≥98% (T)

质量水平

方案

≥95% (HPLC)
≥98% (T)

表单

powder

反应适用性

reagent type: cross-linking reagent
reagent type: linker

官能团

amine
maleimide

聚合物结构设计

functionality: heterobifunctional

SMILES字符串

OC(C(F)(F)F)=O.O=C1N(CCN)C(C=C1)=O

InChI

1S/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)

InChI key

YNHKVOGCDPODMT-UHFFFAOYSA-N

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一般描述

N-(2-氨基乙基)马来酰亚胺三氟乙酸盐是一种硫醇反应性交联剂,用于制备肝素水凝胶[1]

应用

常用的N-(2-氨基乙基)马来酰亚胺三氟乙酸盐用途:
  • 作为交联剂,在聚合物前体之间形成共价键[2]
  • 通过向分子中引入马来酰亚胺官能团,合成马来酰亚胺官能化肝素水凝胶,实现随后的生物结合[3]
  • 合成N-(2-{3-碘苯甲酰}氨乙基)马来酰亚胺和N-的 (2-{3-(三正丁基锡基)苯甲酰基}氨基乙基)马来酰亚胺[4]
  • 作为马来酰亚胺官能化西满烯基衍生物合成中的合成砌块[5]

其他说明

异双功能连接子,用于将马来酰亚胺功能引入广泛使用的NOSu修饰荧光标记中。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand
Bhojani M S, et al.
PLoS ONE, 6(7), e22418-e22418 (2011)
High resolution bioprinting of multi-component hydrogels
R Zimmermann, et al.
Biofabrication, 11, 045008-045008 (2019)
Synthesis and investigation of a radioiodinated F3 peptide analog as a SPECT tumor imaging radioligand
MS Bhojani, et al.
PLoS ONE, 6, e22418-e22418 (2011)
Chemoselective peptide functionalization of starPEG-GAG hydrogels
MV Tsurkan, et al.
Bioconjugate Chemistry, 25, 1942-1950 (2014)
Eduardo Pérez Del Río et al.
Biomaterials, 259, 120313-120313 (2020-08-24)
Recent achievements in the field of immunotherapy, such as the development of engineered T cells used in adoptive cell therapy, are introducing more efficient strategies to combat cancer. Nevertheless, there are still many limitations. For example, these T cells are

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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