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54965

Sigma-Aldrich

(±)-3-羟基丁酸钠

≥99.0% (NT)

别名:

(±)-3-羟基丁酸 钠盐

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About This Item

线性分子式:
CH3CH(OH)CH2COONa
CAS号:
150-83-4
分子量:
126.09
Beilstein:
4824866
EC號碼:
205-774-5
MDL號碼:
MFCD00016716
分類程式碼代碼:
12352100
PubChem物質ID:
57651496
NACRES:
NA.22
价格与库存信息目前不能提供

品質等級

200

化驗

≥99.0% (NT)

mp

167-170 °C

官能基

hydroxyl

SMILES 字串

[Na+].CC(O)CC([O-])=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

InChI 密鑰

NBPUSGBJDWCHKC-UHFFFAOYSA-M

應用

（±）-3-羟基丁酸钠已被用于研究，以了解丁酸盐对成纤维细胞生长因子 21（FGF21）的影响，其参与肝脏中的脂肪酸 β-氧化。[1]它可用于制备聚（3-羟基丁酸酯）。[2]

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL8810
BCCM2157
BCCK8667
BCCJ4209
BCCH2106

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Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Roman Tyzio et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(1), 34-45 (2011-01-07)
GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
Novel synthesis of poly (3-hydroxybutyrate).
Juzwa M and Jedli?ski Z.
Macromolecules, 39(13), 4627-4630 (2006)
Nikolaj Rittig et al.
Shock (Augusta, Ga.), 44(1), 32-35 (2015-04-22)
Endotoxin administrations are used in experimental models of inflammatory disease. Short-term endotoxin tolerance in response to repeated endotoxin exposure is well known, but the duration of endotoxin tolerance in humans remains unknown. The main purpose of this study was to
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Questions

1–2 of 2 Questions  

  1. Is your hydroxybutyrate chemically synthesized or produced from fermentation?

    1 answer

    1. This product is produced from chemical synthesis and fermentation from cell culture. This information is presented on the lot specific Certificate of Origin. Please navigate to the ‘DOCUMENTATION’ section of the Product Detail Page to access a Certificate under the ‘Certificate of Origin’ tab:
      https://www.sigmaaldrich.com/product/aldrich/54965#product-documentation

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  2. What is the ratio of the two isomers in product 54965?

    1 answer

    1. Product 54965 is considered a racemic material, which means that there is approximately a 50/50 ratio of the two isomers. However, it is not tested or characterized, so it cannot be guaranteed to be exactly 50/50, but it should be close.

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