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298360

Sigma-Aldrich

(R)-(-)-3-羟基丁酸 钠盐

optical purity ee: 99% (GLC)

别名:

(R)-(-)-3-羟基丁酸钠盐

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About This Item

线性分子式:
CH3CH(OH)CH2CO2Na
CAS号:
13613-65-5
分子量:
126.09
Beilstein:
6118796
MDL编号:
MFCD00077788
UNSPSC代码:
12352001
PubChem化学物质编号:
24857981
NACRES:
NA.22

表单

solid

质量水平

200

旋光性

[α]22/D −14°, c = 10 in H2O

光学纯度

ee: 99% (GLC)

mp

149-155 °C (lit.)

官能团

hydroxyl

SMILES字符串

[Na+].C[C@@H](O)CC([O-])=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1/t3-;/m1./s1

InChI key

NBPUSGBJDWCHKC-AENDTGMFSA-M

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相关类别

应用

( R )-(-)-3-羟基丁酸钠盐与冠醚反应生成超分子复合物，该复合物可催化 ( S )-丁内酯的区域选择性开环聚合生成 ( R )-3-羟基丁酸低聚物 (OHB)。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCW3884
MKCV4194
0000247184
MKCS1395
0000247184

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Gokel GW
Advances in Supramolecular Chemistry, 7, 61-61 (2001)
Joel S Benjamin et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(1), 125-130 (2016-12-22)
Kabuki syndrome is a Mendelian intellectual disability syndrome caused by mutations in either of two genes (KMT2D and KDM6A) involved in chromatin accessibility. We previously showed that an agent that promotes chromatin opening, the histone deacetylase inhibitor (HDACi) AR-42, ameliorates
Carmen Torres-Esquivel et al.
Frontiers in cellular neuroscience, 14, 547215-547215 (2020-11-12)
Glucose supply from blood is mandatory for brain functioning and its interruption during acute hypoglycemia or cerebral ischemia leads to brain injury. Alternative substrates to glucose such as the ketone bodies (KB), acetoacetate (AcAc), and β-hydroxybutyrate (BHB), can be used
Philip Mm Ruppert et al.
Life science alliance, 4(10) (2021-08-20)
Various forms of fasting and ketogenic diet have shown promise in (pre-)clinical studies to normalize body weight, improve metabolic health, and protect against disease. Recent studies suggest that β-hydroxybutyrate (βOHB), a fasting-characteristic ketone body, potentially acts as a signaling molecule
Christopher J Terranova et al.
Cell reports, 37(8), 110044-110044 (2021-11-25)
β-hydroxybutyrate (β-OHB) is an essential metabolic energy source during fasting and functions as a chromatin regulator by lysine β-hydroxybutyrylation (Kbhb) modification of the core histones H3 and H4. We report that Kbhb on histone H3 (H3K9bhb) is enriched at proximal
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