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437018

Sigma-Aldrich

N-Boc-1,6-己二胺 盐酸盐

97%

别名:

N-(6-氨基己基)氨基甲酸叔丁酯 盐酸盐, N-Boc-1,6-二氨基己烷 盐酸盐

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About This Item

线性分子式:
(CH3)3COCONH(CH2)6NH2 · HCl
CAS号:
65915-94-8
分子量:
252.78
Beilstein:
3631740
EC號碼:
265-976-4
MDL號碼:
MFCD00039072
分類程式碼代碼:
12352116
PubChem物質ID:
24867340
NACRES:
NA.22

化驗

97%

形狀

solid

反應適用性

reagent type: cross-linking reagent

mp

162-164 °C (lit.)

官能基

Boc
amine

SMILES 字串

NCCCCCCNC(OC(C)(C)C)=O.[H]Cl

InChI

1S/C11H24N2O2.ClH/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12;/h4-9,12H2,1-3H3,(H,13,14);1H

InChI 密鑰

JSBWQIZQJOQPFN-UHFFFAOYSA-N

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應用

N-Boc-1,6-hexanediamine hydrochloride is a general reagent to introduce a C6-spacer. It can be used in:
  • Synthesis of poly(L-glutamic acid) gadolinium chelates as biodegradable MRI contrast agents.
  • Synthesis of cholesteryl-functionalized hyaluronic acid-based anionic nanogel for protein delivery.
  • Preparation of amphiphilic prodrug, containing anticancer drug chlorambucil, which would self-assemble to form micelles in aqueous solution.

用于引入 C6 间隔臂的试剂。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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Rational Design of an Amphiphilic Chlorambucil Prodrug Realizing Self-Assembled Micelles for Efficient Anticancer Therapy.
Hu X, et al.
ACS biomaterials science & engineering, 4(3), 973-980 (2018)
Synthesis and characterization of poly (L-glutamic acid) gadolinium chelate: a new biodegradable MRI contrast agent.
Wen X, et al.
Bioconjugate Chemistry, 15(6), 1408-1415 (2004)
Injectable hydrogel for sustained protein release by salt?induced association of hyaluronic acid nanogel.
Nakai T, et al.
Macromolecular Bioscience, 12(4), 475-483 (2012)

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