所有图片(1)
About This Item
线性分子式:
(CH3)3COCONH(CH2)4NH2
CAS号:
分子量:
188.27
Beilstein:
1937878
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22
推荐产品
品質等級
化驗
≥97.0% (GC/NT)
反應適用性
reagent type: cross-linking reagent
折射率
n20/D 1.460
密度
0.984 g/mL at 20 °C (lit.)
官能基
Boc
amine
SMILES 字串
NCCCCNC(OC(C)(C)C)=O
InChI
1S/C9H20N2O2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7,10H2,1-3H3,(H,11,12)
InChI 密鑰
ZFQWJXFJJZUVPI-UHFFFAOYSA-N
應用
- 羧基-硅烷涂覆氧化铁纳米颗粒：详述采用N-Boc-1,4-丁二胺修饰氧化铁纳米颗粒用于成像和药物递送(D Stanicki, S Boutry, S Laurent, et al., 2014)。访问文章。
其他說明
药理活性化合物的制备。亚精胺类似物的制备。C4-间隔基的引入。
訊號詞
Danger
危險聲明
危險分類
Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
228.2 °F - closed cup
閃點（°C）
109.0 °C - closed cup
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
其他客户在看
Regina Holm et al.
Macromolecular rapid communications, 36(23), 2083-2091 (2015-09-08)
In this work, the synthesis of polypeptoid-block-polypeptide copolymers (block copolypept(o)ides) based on bifunctional initiators is described, which introduces a distinct chemical entity at the connection between both blocks. With a view towards redox-sensitive block copolypept(o)ides, a cystamine-based initiator was used
Hongyan Guo et al.
Journal of medicinal chemistry, 45(10), 2056-2063 (2002-05-03)
Several iron chelators containing alpha,beta-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferrioxamine B, acinetoferrin, and nannochelin A) and
Y Shai et al.
Biochemistry, 28(11), 4801-4806 (1989-05-30)
In the present study we synthesize 18F-labeled insulin of high specific radioactivity. A new prosthetic group methodology, in which [18F]fluoride displaces a bromide group of 4-(bromomethyl)-benzoylamine intermediates, was used. The 4-(fluoromethyl)benzoyl product was chemically stable. 18F-Labeled insulin retains the essential
Anand Divakaran et al.
Journal of medicinal chemistry, 61(20), 9316-9334 (2018-09-27)
As regulators of transcription, epigenetic proteins that interpret post-translational modifications to N-terminal histone tails are essential for maintaining cellular homeostasis. When dysregulated, "reader" proteins become drivers of disease. In the case of bromodomains, which recognize N-ε-acetylated lysine, selective inhibition of
Regina Holm et al.
Macromolecular bioscience, 20(1), e1900152-e1900152 (2019-08-21)
RNA interference provides enormous potential for the treatment of several diseases, including cancer. Nevertheless, successful therapies based on siRNA require overcoming various challenges, such as poor pharmacokinetic characteristics of the small RNA molecule and inefficient cytosolic accumulation. In this respect
商品
Mono-Boc-protected diamines are versatile building blocks for chemical synthesis. Their production is a lot more challenging than the simple reaction scheme might imply, because the Boc-anhydride reagent cannot differentiate between the two identical amino moieties in the substrate.
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