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Merck

348015

Sigma-Aldrich

2-氨基苄胺

98%

别名:

(2-氨基甲基苯基)胺, 2-(氨甲基)苯胺, 2-氨基-1-苄胺, 邻氨基苄胺

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About This Item

线性分子式:
H2NC6H4CH2NH2
CAS号:
分子量:
122.17
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

表单

solid

mp

58-61 °C (lit.)

官能团

amine

SMILES字符串

NCc1ccccc1N

InChI

1S/C7H10N2/c8-5-6-3-1-2-4-7(6)9/h1-4H,5,8-9H2

InChI key

GVOYKJPMUUJXBS-UHFFFAOYSA-N

一般描述

2-氨基苯甲胺与 3,3,3-三氟丙酮酸甲酯、2-氨基苯甲胺和氧化合物发生三组分环化反应,得到四氢吡咯并喹唑啉酮的区域和立体异构体。

应用

2-氨基苄胺可用于:
  • 通过与 2-(萘-2-基)-2-氧代乙醛肟的缩合反应,用于 1,2,3,4-四氢喹唑啉肟的合成
  • 合成 烷基 5 H -1,4-苯二氮卓-3-羧酸酯
  • 修饰磷酸丝氨酸肽的磷酸基团

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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G Sirikçi et al.
Acta chimica Slovenica, 59(4), 904-911 (2013-09-26)
A novel 1,2,3,4-tetrahydroquinazoline oxime was synthesised from a condensation reaction of 2-(naphthalen-2-yl)-2-oxoacetaldehyde oxime with 2-aminobenzylamine. Subsequently, a-imine oxime complexes of this compound that formed with Co(III) and Ni(II) metal ions were obtained. All structures were characterised by spectral methods (FT-IR
Wen-Yun Hsueh et al.
Journal of medicinal chemistry, 64(3), 1435-1453 (2021-01-26)
In this paper, we present a copper(I)-catalyzed nitrile-addition/N-arylation ring-closure cascade for the synthesis of 5,11-dihydro-6H-indolo[3,2-c]quinolin-6-ones from 2-(2-bromophenyl)-N-(2-cyanophenyl)acetamides. Using CuBr and t-BuONa in dimethylformamide (DMF) as the optimal reaction conditions, the cascade reaction gave the target products, in high yields, with
Bohumil Dolenský et al.
Magnetic resonance in chemistry : MRC, 48(5), 375-385 (2010-03-20)
A new three-component cyclisation reactions of methyl 3,3,3-trifluoropyruvate, 2-aminobenzylamine and oxo compounds afforded tetrahydropyrroloquinazolinones of the types 4 and 5 as mixtures of regio- and stereoisomers. Whereas standard 1D NMR spectroscopy was used for a facile assignment of the cyclization
Lukas K Filak et al.
Organometallics, 32(3), 903-914 (2013-02-23)
Six novel ruthenium(II)- and osmium(II)-arene complexes with three modified indolo[3,2-c]quinolines have been synthesized in situ starting from 2-aminoindoloquinolines and 2-pyridinecarboxaldehyde in the presence of [M(p-cymene)Cl(2)](2) (M = Ru, Os) in ethanol. All complexes have been characterized by elemental analysis, spectroscopic
Lukas K Filak et al.
Organometallics, 30(2), 273-283 (2011-01-22)
The synthesis of new modified indolo[3,2-c]quinoline ligands L(1)-L(8) with metal-binding sites is reported. By coordination to ruthenium- and osmium-arene moieties 16 complexes of the type [(η(6)-p-cymene)M(L)Cl]Cl (1a,b-8a,b), where M is Ru(II) or Os(II) and L is L(1)-L(8), have been prepared.

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