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191906

Sigma-Aldrich

羟丙基纤维素

average Mw ~1,000,000, powder, 20 mesh particle size (99% through)

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About This Item

CAS号:
9004-64-2
MDL编号:
MFCD00132688
UNSPSC代码:
12162002
NACRES:
NA.23

描述

biological oxygen demand (BOD) 14,000 ppm

表单

powder

自燃温度

752 °F

分子量

average Mw ~1,000,000

杂质

<5 wt. %

粒径

20 mesh (99% through)

pH值（酸碱度）

5.0-8.5

界面张力矿物油

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

粘度

1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)

溶解性

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

密度

0.5 g/mL at 25 °C (lit.)

SMILES字符串

N(C)(C)c1cc(c(cc1)C(N)CC)C

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI key

RRHXDYJWVYFMKV-UHFFFAOYSA-N

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相关类别

应用

  • 热响应性水性泡沫：研究人员已经研究了羟丙基纤维素作为绿色聚合物的性质，它可以随温度变化改变溶解性，适用于响应性泡沫应用 （Braunschweig, 2019）。
  • 水溶液中的相互作用机制：一项有关溶液中羟丙基纤维素和水相互作用的研究，重点关注了聚合物链长在确定溶液物理性质中的重要性 （Martin-Pastor and Stoyanov, 2020）。
  • 腐蚀抑制：研究显示了羟丙基纤维素作为酸性环境中铝腐蚀抑制剂的有效性，重点介绍了其在材料科学和工程应用中的潜力 （Jarkas et al., 2019）。
  • 口腔崩解膜：该应用涉及羟丙基纤维素膜的配方设计，目的在于改善药物的递送和溶出曲线，它在药物递送和药物科学中有重要意义 （Takeuchi et al., 2018）。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCR8693
MKCN0594
MKCD5599
MKBC6263V
MKBJ6793V

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Catherine Boissier et al.
Journal of pharmaceutical sciences, 101(7), 2512-2522 (2012-04-28)
Nuclear magnetic resonance (NMR) cryoporometry and scanning electron microscopy (SEM) image analysis have been used to investigate the size and shape distribution of pores in pharmaceutical coatings. The coatings were made from a mixture of hydroxypropylcellulose (HPC) and ethylcellulose (EC).
Homendra Naorem et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101, 67-73 (2012-10-27)
The formation constant of triiodide ions from iodine-iodide equilibrium in aqueous-organic solvent or polymer mixed media have been determined spectrophotometrically at three different temperatures 20, 30 and 40°C. The organic solvents chosen for the study are ethylene glycol, 2-methoxy ethanol
R Logan et al.
Drug development and industrial pharmacy, 38(11), 1394-1404 (2012-03-23)
Impeller speed was varied from 300 to 1500 rpm during the wet high shear granulation of a placebo formulation using a new vertical shaft PharmaMATRIX-1 granulator. The resulting granules were extensively analysed for differences caused by the varying impeller speed
Ashish Sarode et al.
AAPS PharmSciTech, 14(1), 151-159 (2012-12-20)
Hydroxypropylcellulose (HPC)-SL and -SSL, low-viscosity hydroxypropylcellulose polymers, are versatile pharmaceutical excipients. The utility of HPC polymers was assessed for both dissolution enhancement and sustained release of pharmaceutical drugs using various processing techniques. The BCS class II drugs carbamazepine (CBZ), hydrochlorthiazide
Noorullah Naqvi Mohammed et al.
AAPS PharmSciTech, 13(4), 1158-1169 (2012-09-11)
The objective of this research work was to evaluate Klucel™ hydroxypropylcellulose (HPC) EF and ELF polymers, for solubility enhancement as well as to address some of the disadvantages associated with solid dispersions. Ketoprofen (KPR), a Biopharmaceutics Classification System class II
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