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product name
1-羟基苯并三唑 水合物, wetted with not less than 14 wt. % water, 98% dry basis
品質等級
化驗
98% dry basis
形狀
solid
品質
synthesis grade
反應適用性
reaction type: Addition Reactions
mp
155-158 °C (lit.)
應用
peptide synthesis
SMILES 字串
[H]O[H].On1nnc2ccccc12
InChI
1S/C6H5N3O.H2O/c10-9-6-4-2-1-3-5(6)7-8-9;/h1-4,10H;1H2
InChI 密鑰
PJUPKRYGDFTMTM-UHFFFAOYSA-N
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一般說明
1-羟基苯并三唑水合物是一种苯并三唑衍生物,主要用作肽合成中的偶联剂。
應用
1-羟基苯并三唑水合物可用作以下反应的试剂:
- 通过微波辅助的氨基酸偶联反应合成β-肽。
- 糖肽的点合成。
訊號詞
Danger
危險聲明
危險分類
Aquatic Chronic 3 - Desen. Expl. 2 - Eye Irrit. 2
安全危害
儲存類別代碼
4.1A - Other explosive hazardous materials
水污染物質分類(WGK)
WGK 1
閃點(°F)
314.6 °F
閃點(°C)
157 °C
International journal of peptide and protein research, 42(3), 264-269 (1993-09-01)
3-Dimethylphosphinothioyl-2(3H)-oxazolone (MPTO) was synthesized, and its ability to effect racemization-free couplings and cyclization of a peptide and its C-terminal epimer was examined. MPTO showed good reactivity in aprotic polar solvents such as N,N-dimethylformamide (DMF) and N-methylpyrrolidone. In reactivity MPTO resembles
Synlett, 733-733 (1993)
Tetrahedron Letters, 34, 6383-6383 (1993)
Tetrahedron Letters, 35, 3315-3315 (1994)
Cell chemical biology, 27(9), 1207-1219 (2020-07-02)
Glycan recognition is typically studied using free glycans, but glycopeptide presentations represent more physiological conditions for glycoproteins. To facilitate studies of glycopeptide recognition, we developed Glyco-SPOT synthesis, which enables the parallel production of diverse glycopeptide libraries at microgram scales. The
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