BP1101

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol

British Pharmacopoeia (BP) Reference Standard

• Synonyme(s) : Hydroxychloroquine sulfate, 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
• Formule empirique (notation de Hill): C₁₈H₂₆ClN₃O · H₂SO₄
• Numéro CAS: 747-36-4
• Poids moléculaire : 433.95
• Numéro MDL: MFCD00078203
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Agence: BP
• Famille d'API: hydroxychloroquine
• Forme: solid
• Durée de conservation: limited shelf life, expiry date on the label
• Conditionnement: pkg of 25 mg
• Fabricant/nom de marque: BP
• Conditions de stockage: OK to freeze
• Couleur: off-white
• Pf: 238-241 °C
• Solubilité: water: soluble
• Application(s): pharmaceutical; pharmaceutical small molecule
• Format: neat
• Conditions d'expédition: ambient
• Température de stockage: 2-8°C
• Chaîne SMILES: OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
• Clé InChI: JCBIVZZPXRZKTI-UHFFFAOYSA-N
• Informations sur le gène: human ... TLR7(51284) , TLR9(54106)

Description

Description générale

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol (Hydroxychloroquine Sulfate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Actions biochimiques/physiologiques

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

Conditionnement

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H315,H319
• Conseils de prudence: P264 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable