PHR1258

Chloroquine phosphate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : Chloroquine diphosphate salt, N⁴-(7-Chloro-4-quinolinyl)-N¹,N¹-dimethyl-1,4-pentanediamine diphosphate salt
• Formule empirique (notation de Hill): C₁₈H₂₆ClN₃ · 2H₃PO₄
• Numéro CAS: 50-63-5
• Poids moléculaire : 515.86
• Numéro Beilstein : 4223142
• Numéro CE : 200-055-2
• Numéro MDL: MFCD00069852
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823259
• Nomenclature NACRES : NA.24

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 300
• Qualité: certified reference material; pharmaceutical secondary standard
• Agence: BP; EP; USP; traceable to USP 1118000
• Pression de vapeur: <0.0000001 kPa ( 25 °C)
• Famille d'API: chloroquine
• CofA (certificat d'analyse): current certificate can be downloaded
• Conditionnement: pkg of 1 g
• Conditions de stockage: protect from light
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Couleur: white to yellow
• pH: 3.5-4.5 (10% in aqueous solution, pH <6.0)
• Pf: 200 °C (dec.) (lit.)
• Solubilité: water: 50 g/L; benzene: practically insoluble; chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: OP(O)(O)=O.OP(O)(O)=O.CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
• Clé InChI: QKICWELGRMTQCR-UHFFFAOYSA-N

Description

Description générale

Chloroquine phosphate is a phosphate salt of chloroquine. It belongs to the class of aminoquinoline drugs utilized as antimalarials and amebicides.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Chloroquine phosphate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin-layer chromatography (TLC) and liquid chromatography (LC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAB3715 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable