N8410

β-Nicotinamide adenine dinucleotide

pkg of 20 mg (per vial)

• Synonyme(s) : β-DPN, β-NAD, Coenzyme 1, Cozymase, DPN, Diphosphopyridine nucleotide, Nadide
• Formule empirique (notation de Hill): C₂₁H₂₇N₇O₁₄P₂
• Numéro CAS: 53-84-9
• Poids moléculaire : 663.43
• Numéro Beilstein : 3584133
• Numéro CE : 200-184-4
• Numéro MDL: MFCD00036253
• Code UNSPSC : 41106305
• eCl@ss : 39200202
• ID de substance PubChem : 329818687
• Nomenclature NACRES : NA.51

Propriétés

• Forme: powder
• Niveau de qualité: 200
• Conditionnement: pkg of 20 mg (per vial)
• Température de stockage: −20°C
• Chaîne SMILES: NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
• InChI: 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• Clé InChI: BAWFJGJZGIEFAR-NNYOXOHSSA-N

Description

Application

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

β-Nicotinamide adenine dinucleotide has been used in the master mix for coupled enzyme assay to estimate pectin methylesterase activity.

Actions biochimiques/physiologiques

β-Nicotinamide adenine dinucleotide (β-NADH) reduced form is an essential cofactor in all the living organisms. β-NADH functions as a hydride acceptors in biochemical redox reactions. It acts as a cell signaling molecule and is a potent neurotransmitter and neuromodulator in the peripheral nervous system. In brain, it mediates Ca²⁺ homeostasis, energy metabolism, aging and neuronal death.

Electron acceptor

Autres remarques

Packaged based on NAD content as determined by UV-Vis.

This is the common form of NAD.

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)