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914460

Sigma-Aldrich

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride

≥95%

Synonyme(s) :

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride, N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide hydrochloride, N-{2-[2-(2- Aminoethoxy)ethoxy]ethoxy}biotinamide hydrochloride, Amine-terminated biotin linker, Biotin-DOOA HCl, Biotinylation reagent

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About This Item

Formule empirique (notation de Hill):
C16H31ClN4O4S
Numéro CAS:
862373-14-6
Poids moléculaire :
410.96
Code UNSPSC :
12352116
Nomenclature NACRES :
NA.22

Niveau de qualité

100

Pureté

≥95%

Forme

powder

Température de stockage

2-8°C

Application

1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride is a versatile biotinylated linker that can be incorporated into chemical tools via its terminal amino group. Labeling materials or proteins with biotin provides a means to enrich and capture targets from biological systems.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Autres remarques

Efficient Innate Immune Killing of Cancer Cells Triggered by Cell Surface Anchoring of Multivalent Antibody-Recruiting Polymers

Caged Cyclopropenes with Improved Tetrazine Ligation Kinetics

A Unified Framework for the Incorporation of Bioorthogonal Compound Exposure Probes within Biological Compartments

A Chemical Probe for Protein Crotonylation

One-Step Selective Exoenzymatic Labeling (SEEL) Strategy for the Biotinylation and Identification of Glycoproteins of Living Cells

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

T2879

Tyramine hydrochloride, ≥98%

H1759

(+)-Biotin N-hydroxysuccinimide ester, ≥98% (HPLC), powder

B7639

(+)-Biotin hydrazide, ≥97% (TLC), powder

B5768

Biotin 4-amidobenzoic acid sodium salt, ≥95%

14400

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861650

(+)-Biotin 4-nitrophenyl ester, 98%

B2059

Biotin Polyethyleneoxide Iodoacetamide

764213

Biotin-PEG4-alkyne, for copper catalyzed click labeling

QBD10196

Biotin-dPEG®11-NH2

QBD10826

Biotin-dPEG®7-NH2

SML2135

Biotinyl tyramide, ≥97% (HPLC)

914916

Biotin-SS-tyramide, ≥95%

914134

5-(Biotinamido)pentylamine TFA Salt, ≥95%

914924

3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid, ≥95%

913669

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
MKCV2608
MKCV1544
MKCM4406

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Benjamin Spangler et al.
ACS infectious diseases, 4(9), 1355-1367 (2018-05-31)
The Gram-negative cell envelope presents a formidable barrier to xenobiotics, and achieving sufficient compound exposure inside the cell is a key challenge for the discovery of new antibiotics. To provide insight on the molecular determinants governing compound exposure in Gram-negative
Kosuke Chiba et al.
Chemical communications (Cambridge, England), 53(62), 8751-8754 (2017-07-21)
We herein propose a simple affinity-labeling method using a ligand-4-azidophthalimide (AzPI) conjugate. As a proof of concept, we show that two different ligand-AzPI conjugates enabled highly specific fluorescence labeling of their individual target proteins even in crude cell lysates. This
Annemiek Uvyn et al.
Angewandte Chemie (International ed. in English), 58(37), 12988-12993 (2019-06-18)
Binding of monoclonal antibodies (mAbs) onto a cell surface triggers antibody-mediated effector killing by innate immune cells through complement activation. As an alternative to mAbs, synthetic systems that can recruit endogenous antibodies from the blood stream to a cancer cell
Wilke C de Vries et al.
ACS applied materials & interfaces, 9(48), 41760-41766 (2017-11-16)
We present the preparation of ligand-conjugated redox-responsive polymer nanocontainers by the supramolecular decoration of cyclodextrin vesicles with a thin redox-cleavable polymer shell that displays molecular recognition units on its surface. Two widely different recognition motifs (mannose-Concanavalin A and biotin-streptavidin) are
Zhiyuan Fang et al.
Chemical communications (Cambridge, England), 49(55), 6164-6166 (2013-06-04)
A direct ELISA was established for the fast detection of semicarbazide (SEM) using a novel biotin derivative. Without a tedious extraction procedure, as low as 0.07 μg L(-1) of SEM could be detected reproducibly. This assay has better recovery and
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