900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

• Synonyme(s) : Hydroxyl diazirine TMS-alkyne, Probe building block
• Formule empirique (notation de Hill): C₁₄H₁₅F₃N₂OSi
• Numéro CAS: 2187374-13-4
• Poids moléculaire : 312.36
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: ≥95%
• Forme: powder or crystals
• Température de stockage: −20°C
• Chaîne SMILES: OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

Description

Application

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Autres remarques

Technology Spotlight: Trifunctional Probe Building Blocks

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable