900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Synonyme(s) : Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• Formule empirique (notation de Hill): C₁₁H₁₂BrFO₂SSi
• Numéro CAS: 2088829-15-4
• Poids moléculaire : 335.26
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: ≥95%
• Forme: powder or crystals
• Capacité de réaction: reaction type: click chemistry
• Température de stockage: −20°C

Description

Application

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Autres remarques

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable