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409510

Sigma-Aldrich

Poly(ethylene glycol) dimethacrylate

average MN 550, cross-linking reagent polymerization reactions, methacrylate, 80-120 ppm MEHQ as inhibitor, 270-330 ppm BHT as inhibitor

Synonyme(s) :

Polyethylene glycol, PEG dimethacrylate

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About This Item

Formule linéaire :
C3H5C(O)(OCH2CH2)nOC(O)C3H5
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12162002
ID de substance PubChem :
Nomenclature NACRES :
NA.23

product name

Poly(ethylene glycol) dimethacrylate, average Mn 550, contains 80-120 ppm MEHQ as inhibitor, 270-330 ppm BHT as inhibitor

Forme

liquid

Niveau de qualité

Poids mol.

average Mn 550

Contient

270-330 ppm BHT as inhibitor
80-120 ppm MEHQ as inhibitor

Pertinence de la réaction

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

Indice de réfraction

n20/D 1.466

Point d'ébullition

>200 °C/2 mmHg (lit.)

Densité

1.099 g/mL at 25 °C

Extrémité Ω

methacrylate

Extrémité α

methacrylate

Architecture des polymères

shape: linear
functionality: homobifunctional

Température de stockage

2-8°C

Chaîne SMILES 

OCCO.CC(=C)C(O)=O

InChI

1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3

Clé InChI

STVZJERGLQHEKB-UHFFFAOYSA-N

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Application


  • PDGF-AA loaded photo-crosslinked chitosan-based hydrogel for promoting wound healing.: This study investigates the use of a chitosan-based hydrogel, photo-crosslinked with Poly(ethylene glycol) dimethacrylate (PEGDMA), to deliver PDGF-AA and enhance wound healing. The results demonstrate significant improvements in wound closure rates and tissue regeneration (Cai et al., 2024).

  • Reducing the foreign body response on human cochlear implants and their materials in vivo with photografted zwitterionic hydrogel coatings.: This research explores the application of PEGDMA in zwitterionic hydrogel coatings to minimize foreign body responses in cochlear implants. The coatings significantly reduced inflammation and improved biocompatibility in vivo (Horne et al., 2023).

  • Full factorial design of experiment-based and response surface methodology approach for evaluating variation in uniaxial compressive mechanical properties, and biocompatibility of photocurable PEGDMA-based scaffolds.: This study uses a full factorial design to optimize the mechanical properties and biocompatibility of PEGDMA-based scaffolds, highlighting their potential use in tissue engineering and regenerative medicine (Bharadwaz et al., 2023).

  • Antifouling and Mechanical Properties of Photografted Zwitterionic Hydrogel Thin-Film Coatings Depend on the Cross-Link Density.: This article examines how varying the cross-link density in PEGDMA-based hydrogel coatings affects their antifouling and mechanical properties. The findings are relevant for the development of durable and biocompatible medical device coatings (Jensen et al., 2021).

  • Biocompatible and photocrosslinkable poly(ethylene glycol)/keratin biocomposite hydrogels.: The research presents the development of PEGDMA/keratin biocomposite hydrogels, demonstrating excellent biocompatibility and potential applications in drug delivery systems and tissue engineering (Wang et al., 2021).

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Laura Ferlauto et al.
Frontiers in neuroscience, 12, 648-648 (2018-10-05)
Reducing the mechanical mismatch between the stiffness of a neural implant and the softness of the neural tissue is still an open challenge in neuroprosthetics. The emergence of conductive hydrogels in the last few years has considerably widened the spectrum
Albert H Park et al.
The Laryngoscope, 123(4), 1043-1048 (2013-03-21)
To determine the resorption rate and biocompatibility characteristics of novel cross-linked hydrogel ventilation tubes and varied formulations of polyester ventilation tubes in a Chinchilla model. Animal Study. Three cross-linked glycosaminoglycan hydrogel ventilation tubes fabricated by cross-linking thiol-modified chondroitin sulfate or
Craig Halberstadt et al.
Methods in molecular biology (Clifton, N.J.), 1001, 279-287 (2013-03-16)
Delivery of cells to organs has primarily relied on formulating the cells in a nonviscous liquid carrier. We have developed a methodology to isolate selected renal cells (SRC) that have provided functional stability to damaged kidneys in preclinical models (Kelley
Katarzyna Kotynia et al.
Polimery w medycynie, 43(1), 21-28 (2013-07-03)
PURPOSE OF JOB: Currently, there isa need to increase comfort and visual acuity man. Simultaneously improving biocompatibility and minimizing the impact of the material on the physiology of the cornea is the primary driving force behind the evolution of materials
Kenneth C Koehler et al.
Biomaterials, 34(16), 4150-4158 (2013-03-08)
We report a new approach to controlled drug release based upon exploiting the dynamic equilibrium that exists between Diels-Alder reactants and products, demonstrating the release of a furan containing dexamethasone peptide (dex-KGPQG-furan) from a maleimide containing hydrogel. Using a reaction-diffusion

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