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Key Documents

SRP0440

Sigma-Aldrich

UBE1 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)

Synonym(e):

UBA1, UBA1A, ubiquitin-like modifier activating enzyme 1

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About This Item

UNSPSC-Code:
12352200
NACRES:
NA.32

Biologische Quelle

human

Rekombinant

expressed in baculovirus infected Sf9 cells

Assay

≥80% (SDS-PAGE)

Form

aqueous solution

Mol-Gew.

118 kDa

Verpackung

pkg of 100 μg

NCBI-Hinterlegungsnummer

NM_003334

UniProt-Hinterlegungsnummer

P22314

Versandbedingung

dry ice

Lagertemp.

−70°C

Angaben zum Gen

human ... UBA1(7317)

Allgemeine Beschreibung

Human UBE1 (GenBank Accession No. NM_003334) amino-acids 2-end with N-terminal FLAG-tag, MW=118 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Anwendung

Useful in conjunction with E2 and E3 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Yu-Hui Li et al.
Experimental cell research, 371(1), 250-254 (2018-08-18)
Ninety percent of all cancer related deaths happen due to metastatic progression. One important protein facilitating metastatic progression in hepatocellular carcinoma (HCC) is the metastasis associated 1 protein (MTA-1). We have earlier shown that in the context of HCC and
Juliane Ramser et al.
American journal of human genetics, 82(1), 188-193 (2008-01-09)
X-linked infantile spinal muscular atrophy (XL-SMA) is an X-linked disorder presenting with the clinical features hypotonia, areflexia, and multiple congenital contractures (arthrogryposis) associated with loss of anterior horn cells and infantile death. To identify the XL-SMA disease gene, we performed
Yi Liu et al.
Journal of experimental botany, 71(18), 5562-5576 (2020-05-27)
Plants can be simultaneously exposed to multiple stresses. The interplay of abiotic and biotic stresses may result in synergistic or antagonistic effects on plant development and health. Temporary drought stress can stimulate plant immunity; however, the molecular mechanism of drought-induced
UBE1 expression in extranodal NK/T cell lymphoma, nasal type.
Z L Su et al.
Leukemia & lymphoma, 49(9), 1821-1822 (2008-07-29)
J Romaní-Aumedes et al.
Cell death & disease, 5, e1364-e1364 (2014-08-08)
Mutations in the PARK2 gene are associated with an autosomal recessive form of juvenile parkinsonism (AR-JP). These mutations affect parkin solubility and impair its E3 ligase activity, leading to a toxic accumulation of proteins within susceptible neurons that results in
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