SML3597

ARUK3001185

≥98% (HPLC)

• Synonym(e): 1-[2,4-Dichloro-3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole
• Empirische Formel (Hill-System): C₉H₄Cl₂F₃N₃
• CAS-Nummer: 2411969-39-4
• Molekulargewicht: 282.05
• UNSPSC-Code: 12352200
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: -10 to -25°C
• SMILES String: ClC1=C(C(Cl)=CC=C1N2C=CN=N2)C(F)(F)F

Beschreibung

Biochem./physiol. Wirkung

ARUK3001185 is a brain-penetrant, orally available, potent and selective carboxylesterase Notum inhibitor (IC50 = 6.7 nM) and Wnt signaling activator with no cross-reactivity toward panels of 39 serine hydrolases, 485 kinases (IC50 >10 μM), and 47 human off-target liabilities (IC50 >30 μM).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable