SML1284

Efavirenz Ready Made Solution

10 mg/mL in DMSO

• Synonym(e): (4S)-6-Chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one, (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
• Empirische Formel (Hill-System): C₁₄H₉ClF₃NO₂
• CAS-Nummer: 154598-52-4
• Molekulargewicht: 315.67
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Form: DMSO solution
• Qualitätsniveau: 200
• Konzentration: 10 mg/mL in DMSO
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: FC(F)(F)[C@]2(OC(=O)Nc3c2cc(cc3)Cl)C#CC1CC1
• InChI: 1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
• InChIKey: XPOQHMRABVBWPR-ZDUSSCGKSA-N

Beschreibung

Biochem./physiol. Wirkung

Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI). Efavirenz is an anti-HIV drug, commonly used in combination therapy for AIDs treatment. Efavirenz is part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.

The plasma levels of this drug can determine the failure of treatment and CNS (central nervous system) side-effects in patients infected with HIV (human immunodeficiency virus).

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H360,H411
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Gefahreneinstufungen: Aquatic Chronic 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): 188.6 °F
• Flammpunkt (°C): 87 °C