SML0331

Prasugrel

≥98% (HPLC)

• Synonym(e): 5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate, CS 747, CS-747, Effient, Efient, LY640315
• Empirische Formel (Hill-System): C₂₀H₂₀FNO₃S
• CAS-Nummer: 150322-43-3
• Molekulargewicht: 373.44
• MDL-Nummer: MFCD09954140
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825336
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: >5 mg/mL (warmed at 60 °C)
• Lagertemp.: 2-8°C
• SMILES String: CC(=O)Oc1cc2CN(CCc2s1)C(C(=O)C3CC3)c4ccccc4F
• InChI: 1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3
• InChIKey: DTGLZDAWLRGWQN-UHFFFAOYSA-N
• Angaben zum Gen: human ... P2RY12(64805)

Beschreibung

Biochem./physiol. Wirkung

Prasugrel is a platelet inhibitor that reduces the aggregation of platelets by irreversible binding to P2Y12 receptors. Prasugrel interacts in an irreversible manner with the residues Cys97 and Cys175 of the human P2Y12-receptor.

Prasugrel is a thienopyridine prodrug and is considered to be more potent than clopidogrel. It shows a faster generation and also reduces thrombotic events. Prasugrel is less dependent on the CYP (cytochrome P450) enzymes for its conversion to active metabolite.

Leistungsmerkmale und Vorteile

This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable