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Merck

SAB5300165

Sigma-Aldrich

Monoclonal Anti-OVA antibody produced in mouse

clone 3G2E1D9, ascites fluid

Synonym(e):

N/A

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

3G2E1D9, monoclonal

Methode(n)

direct ELISA: 1:10,000
western blot: 1:500-1:2,000

Isotyp

IgG1

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes.

Immunogen

Ovalbumin
Mouse monoclonal antibody raised against OVA

Biochem./physiol. Wirkung

Ovalbumin (OVA) peptide 323-339 mediates 25-35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation. It is extensively used in allergy research.

Physikalische Form

Ascitic fluid containing 0.03% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Keigo Kondou et al.
Journal of biological engineering, 13, 77-77 (2019-10-28)
The baculovirus (BV) Autographa californica multiple nuclear polyhedrosis virus has been used in numerous protein expression systems because of its ability to infect insect cells and serves as a useful vaccination vector with several benefits, such as its low clinical
Ingrid S Zeelenberg et al.
Cancer research, 68(4), 1228-1235 (2008-02-19)
Expression of non-self antigens by tumors can induce activation of T cells in vivo, although this activation can lead to either immunity or tolerance. CD8+ T-cell activation can be direct (if the tumor expresses MHC class I molecules) or indirect
Comparison between ovalbumin and ovalbumin peptide 323-339 responses in allergic mice: humoral and cellular aspects.
Sun LZ
Scandinavian Journal of Immunology, 71(5), 329-335 (2010)
Tian-Yu Song et al.
Nature communications, 12(1), 7003-7003 (2021-12-03)
Cancer cells acquire genetic heterogeneity to escape from immune surveillance during tumor evolution, but a systematic approach to distinguish driver from passenger mutations is lacking. Here we investigate the impact of different immune pressure on tumor clonal dynamics and immune

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