S9132

Spiramycin

• Synonym(e): Formacidin
• CAS-Nummer: 8025-81-8
• EG-Nummer: 232-429-6
• MDL-Nummer: MFCD01314545
• UNSPSC-Code: 51283208
• PubChem Substanz-ID: 24899826
• NACRES: NA.85

Eigenschaften

• Form: powder
• Qualitätsniveau: 200
• Optische Aktivität: [α]/D -85 to -80° in water (Specific rotation (dry basis))
• Wirksamkeit: ≥4100 I.U. per mg (dry basis)
• Lagerbedingungen: (Keep container tightly closed in a dry and well-ventilated place.)
• Farbe: white to light yellow
• Löslichkeit: methanol: soluble
• Kationenspuren: heavy metals: ≤20 ppm
• Wirkungsspektrum von Antibiotika: Gram-positive bacteria
• Wirkungsweise: protein synthesis | interferes
• Lagertemp.: 2-8°C
• SMILES String: CO[C@H]1[C@H](O)CC(=O)O[C@H](C)C\C=C\C=C\[C@H](OC2CCC(C(C)O2)N(C)C)[C@H](C)C[C@H](CC=O)[C@@H]1OC3OC(C)C(OC4CC(C)(O)C(O)C(C)O4)C(C3O)N(C)C
• InChI: 1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
• InChIKey: ACTOXUHEUCPTEW-JMRHEKERSA-N

Beschreibung

Allgemeine Beschreibung

Chemical structure: macrolide

Anwendung

Spiramycin is a macrolide antibiotic that is commonly used to treat infections of soft tissues. It has been used to treat bronchopulmonary infections in adults and has been used to study septicemia in mice .

Biochem./physiol. Wirkung

Spiramycin is a 16-membered ring macrolide antibiotic from Streptomyces ambofaciens. It inhibits bacterial protein synthesis at the level of peptidy-tRNA dissociation from ribosomes. It is mainly used against Gram-positive bacteria.

Qualität

A mixture of Spiramycin I, II and III.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)