S7900

Saponin aus Quillaja Rinde

Sapogenin content ≥10 %

• CAS-Nummer: 8047-15-2
• EG-Nummer: 232-462-6
• MDL-Nummer: MFCD00081981
• UNSPSC-Code: 12161902
• NACRES: NA.32

Eigenschaften

• Beschreibung: non-ionic
• Qualitätsniveau: 200
• Zusammensetzung: Sapogenin content, ≥10%
• Methode(n): HPLC: suitable; protein quantification: suitable
• Sulfatasche: <20%

Beschreibung

Allgemeine Beschreibung

Saponins are natural steroidal glycoside (terpenes).

Anwendung

Saponin from Quillaja bark has been used:

• to stain CD4⁺ and CD8⁺ T-cells
• to lyse trophozoite-infected red blood cells
• in immunohistochemical staining

Biochem./physiol. Wirkung

Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Hence it is used as vaccine adjuvants. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects.

Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro.

Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves