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P6534
Phospholipase A2 aus Schweinepankreas
ammonium sulfate suspension, ≥600 units/mg protein
Synonym(e):
Lecithinase A, PLA2
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About This Item
Empfohlene Produkte
Form
ammonium sulfate suspension
Qualitätsniveau
Spezifische Aktivität
≥600 units/mg protein
UniProt-Hinterlegungsnummer
Lagertemp.
2-8°C
Angaben zum Gen
pig ... PLA2G1B(445525)
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Allgemeine Beschreibung
Phospholipase A2 is a small disulfide-rich protein having 124 residues. It is a calcium-dependent enzyme.
Anwendung
Phospholipase A2 has been used in phospholipase assay and to determine rat renal proximal tubular segments (PTS) viability during oxygenation and hypoxia-reoxygenation.
Biochem./physiol. Wirkung
It has a high catalytic activity on aggregated substrates compared to monomeric substrates.
Hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. Aggressively attacks phospholipids in membranes of intact cells.
Einheitendefinition
1 U hydrolysiert 1.0 μmol Soja L-α-Phosphatidylcholin zu L-α-Lysophosphatidylcholin und Fettsäure pro Minute bei pH 8.0 und 37 °C.
Physikalische Form
Suspension in 3.2 M (NH4)2SO4-Lösung, pH 5.5
Hinweis zur Analyse
Proteingehalt mittels Biuret-Reaktion bestimmt.
Inhibitor
Produkt-Nr.
Beschreibung
Preisangaben
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
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