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Merck

MAK109

Sigma-Aldrich

LPL Activity Assay Kit

Supplied by Roar Biomedical, Inc.

Synonym(e):

Lipoprotein lipase activity assay kit

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About This Item

UNSPSC-Code:
12161503
NACRES:
NA.84

Verwendung

sufficient for 100 fluorometric tests

Anwendung(en)

pharmaceutical

Nachweisverfahren

fluorometric

Relevante Krankheit(en)

gastrointestinal diseases; cardiovascular diseases

Lagertemp.

2-8°C

Angaben zum Gen

human ... LPL(4023)

Allgemeine Beschreibung

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.

Anwendung

LPL Activity Assay Kit may be used for detection of LPL activity in plasma samples of patients with hypertriglyceridemia.

Eignung

Suitable for the measurement of lipoprotein lipase activity in a variety of tissue samples

Prinzip

The LPL Activity Assay Kit includes a non-fluorescent substrate emulsion that becomes intensely fluorescent upon interaction with LPL and pre-hydrolyzed substrate for use as a standard to convert the fluorescence intensity reading to moles of reactant formed (λEx=370 nm/λEm=450 nm). The assay is not specific for LPL and will also detect hepatic lipase activity.

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Lagerklassenschlüssel

10 - Combustible liquids


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Maria Notarnicola et al.
Lipids in health and disease, 11, 145-145 (2012-11-01)
Lipid metabolism is altered in subjects with liver steatosis. FAS is a key enzyme in de novo lipogenesis and both FAS gene expression and enzymatic activity are primarily regulated by metabolic signals in the liver. Lipoprotein lipase (LPL), the rate-limiting
Cedric H L Shackleton
Lipids, 47(1), 1-12 (2011-08-30)
In 1937 Butler and Marrian found large amounts of the steroid pregnanetriol in urine from a patient with the adrenogenital syndrome, a virilizing condition known to be caused by compromised adrenal secretion even in this pre-cortisol era. This introduced the
Ewa Szalowska et al.
Peptides, 32(5), 938-945 (2011-02-22)
GIP receptor knockout mice were shown to be protected from the development of obesity on a high fat diet, suggesting a role of GIP in the development of obesity. In our study we aimed to test the hypothesis if excess
Evemie Dubé et al.
Biology of reproduction, 87(1), 14-14 (2012-05-04)
Knowledge of the consequences of maternal obesity in human placental fatty acids (FA) transport and metabolism is limited. Animal studies suggest that placental uptake of maternal FA is altered by maternal overnutrition. We hypothesized that high maternal body mass index
Tomomi Yamazaki et al.
Journal of lipid research, 53(10), 2024-2037 (2012-06-28)
Postprandial hyperlipidemia (lipemia) is a risk factor for atherosclerosis. However, mouse models of postprandial hyperlipidemia have not been reported. Here, we report that ddY mice display marked postprandial hypertriglyceridemia in response to dietary fat. In ddY mice, the fasting serum

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