L5139

Lycorine hydrochloride

powder, ≥98% (TLC)

• Synonym(e): Licorin hydrochloride, Lychorine chloride, Lycorine HCl
• Empirische Formel (Hill-System): C₁₆H₁₇NO₄ · HCl
• CAS-Nummer: 2188-68-3
• Molekulargewicht: 323.77
• MDL-Nummer: MFCD00243111
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24896395
• NACRES: NA.77

Eigenschaften

• product name: Lycorine hydrochloride, ≥98% (TLC), powder
• Qualitätsniveau: 100
• Assay: ≥98% (TLC)
• Form: powder
• mp (Schmelzpunkt): 210-212 °C
• Löslichkeit: ethanol: 10 mg/mL, clear, colorless to very faintly yellow
• Lagertemp.: 2-8°C
• SMILES String: Cl.O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@H]([C@@H]1O)[C@@H]23
• InChI: 1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1
• InChIKey: VUVNTYCHKZBOMV-NVJKKXITSA-N

Beschreibung

Biochem./physiol. Wirkung

A selective inhibitor of peptidyl transferase center (PTC). In HL-60 (leukemia) cells, lycorine arrests the cell cycle at G2/M and induces apoptosis by a caspase-mediated pathway.

Vorsicht

vor Licht schützen

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges