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N8133

Sigma-Aldrich

Nerve Growth Factor from Vipera lebetina venom

lyophilized powder, suitable for cell culture

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About This Item

CAS-Nummer:
9061-61-4
MDL-Nummer:
MFCD00147703
UNSPSC-Code:
12352202
NACRES:
NA.77

product name

Nerve Growth Factor from Vipera lebetina venom, NGF, lyophilized powder, suitable for cell culture

Biologische Quelle

Vipera Lebetina

Qualitätsniveau

200

Form

lyophilized powder

Wirksamkeit

0.2-20 μg/mL ED50/EC50

Qualität

endotoxin tested

Mol-Gew.

protein 32.5 kDa

Verpackung

pkg of 0.1 mg

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

<10 EU/vial

Farbe

white to off-white

UniProt-Hinterlegungsnummer

P25428

Lagertemp.

−20°C

Verwandte Kategorien

Physikalische Form

Lyophilized from a 0.2 μm filtered solution in sodium acetate buffer.

Angaben zur Herstellung

Isolated from the snake venom of V. lebetina.

Hinweis zur Analyse

The biological activity of Nerve Growth Factor (NGF) from Vipera lebetina venom is measured in a cell proliferation assay using PC-12 cells.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Cytarabin United States Pharmacopeia (USP) Reference Standard

USP

1162002

Cytarabin

Lucy Hepburn et al.
Science (New York, N.Y.), 346(6209), 641-646 (2014-11-02)
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand Spaetzle is not thought to have a vertebrate equivalent. We have found that the structurally related cystine-knot protein, nerve growth factor
Rachel T Uren et al.
Journal of neurochemistry, 129(4), 614-627 (2014-02-04)
Suppressor of cytokine signaling-2 (SOCS2) is a regulator of intracellular responses to growth factors and cytokines. Cultured dorsal root ganglia neurons from neonatal mice with increased or decreased SOCS2 expression were examined for altered responsiveness to nerve growth factor (NGF).
Giusi Prencipe et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 3345-3354 (2014-03-04)
Nerve growth factor (NGF) levels are highly increased in inflamed tissues, but their role is unclear. We show that NGF is part of a regulatory loop in monocytes: inflammatory stimuli, while activating a proinflammatory response through TLRs, upregulate the expression
Jeremy E Purvis et al.
Cell, 152(5), 945-956 (2013-03-05)
A growing number of studies are revealing that cells can send and receive information by controlling the temporal behavior (dynamics) of their signaling molecules. In this Review, we discuss what is known about the dynamics of various signaling networks and
Geraldine Longo et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(24), 10066-10074 (2013-06-14)
Although chronic pain is the most common symptom of arthritis, relatively little is known about the mechanisms driving it. Recently, a sprouting of autonomic sympathetic fibers into the upper dermis of the skin, an area that is normally devoid of
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