H6501

DL-β-Hydroxybuttersäure Natriumsalz

~98%, powder

• Synonym(e): (±)-3-Hydroxybuttersäure Natriumsalz
• Lineare Formel: C₄H₇O₃Na
• CAS-Nummer: 150-83-4
• Molekulargewicht: 126.09
• EG-Nummer: 205-774-5
• MDL-Nummer: MFCD00016716
• UNSPSC-Code: 12352204
• PubChem Substanz-ID: 24895744
• NACRES: NA.83

Eigenschaften

• product name: DL-β-Hydroxybuttersäure Natriumsalz, ~98%
• Assay: ~98%
• Qualitätsniveau: 200
• Form: powder
• Löslichkeit: water: 1 g/10 mL, clear, colorless
• Lagertemp.: 2-8°C
• SMILES String: [Na].CC(O)CC(O)=O
• InChI: 1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
• InChIKey: NBPUSGBJDWCHKC-UHFFFAOYSA-M

Beschreibung

Anwendung

DL-β-Hydroxybutyric acid sodium salt has been used:

• as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows
• to investigate its anticonvulsant effects in epilepsy induced rats
• to induce hyperketonemia in Holstein dairy cows

Biochem./physiol. Wirkung

β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD⁺, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)