F124

Furafylline

≥98% (HPLC), powder, caffeine inhibitor

• Synonym(e): 3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione
• Empirische Formel (Hill-System): C₁₂H₁₂N₄O₃
• CAS-Nummer: 80288-49-9
• Molekulargewicht: 260.25
• MDL-Nummer: MFCD00153799
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24278813
• NACRES: NA.77

Eigenschaften

• product name: Furafylline, ≥98% (HPLC)
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• mp (Schmelzpunkt): 274-275 °C
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: room temp
• SMILES String: CN1C(=O)N(Cc2ccco2)c3nc(C)[nH]c3C1=O
• InChI: 1S/C12H12N4O3/c1-7-13-9-10(14-7)16(6-8-4-3-5-19-8)12(18)15(2)11(9)17/h3-5H,6H2,1-2H3,(H,13,14)
• InChIKey: KGQZGCIVHYLPBH-UHFFFAOYSA-N
• Angaben zum Gen: human ... CYP1A2(1544)

Beschreibung

Biochem./physiol. Wirkung

Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.

Furafylline is a methyl xanthine derivative with longer duration of action than theophylline and an inhibitor of cytochrome P4501A2.

Leistungsmerkmale und Vorteile

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)