E7879

β-17-Estradiol-Acetat

≥99%

• Synonym(e): 1,3,5(10)-Estratrien-3,17β-diol-17-acetat, 3,17β-Dihydroxy-1,3,5(10)-estratrien-17-acetat
• Empirische Formel (Hill-System): C₂₀H₂₆O₃
• CAS-Nummer: 1743-60-8
• Molekulargewicht: 314.42
• Beilstein: 2625732
• MDL-Nummer: MFCD00056537
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24894658
• NACRES: NA.77

Eigenschaften

• Sterilität: non-sterile
• Qualitätsniveau: 200
• Assay: ≥99%
• Form: powder
• Löslichkeit: chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C
• InChI: 1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1
• InChIKey: QAHOQNJVHDHYRN-SLHNCBLASA-N

Beschreibung

Anwendung

β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.

Biochem./physiol. Wirkung

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

Leistungsmerkmale und Vorteile

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H360FD,H410
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Gefahreneinstufungen: Aquatic Chronic 1 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges