D9069

N-Desmethyltamoxifen HCl

≥98% (HPLC), solid

• Synonym(e): (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, ICI 55,548
• Empirische Formel (Hill-System): C₂₅H₂₇NO·HCl
• CAS-Nummer: 15917-65-4
• Molekulargewicht: 393.95
• MDL-Nummer: MFCD03423594
• UNSPSC-Code: 12352203
• PubChem Substanz-ID: 329798889
• NACRES: NA.77

Eigenschaften

• Sterilität: non-sterile
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: solid
• Lagerbedingungen: desiccated
• Methode(n): inhibition assay: suitable
• Löslichkeit: DMSO: ≥20 mg/mL
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3
• InChI: 1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
• InChIKey: GMLHJWZEYLTNJW-BJFQDICYSA-N

Beschreibung

Anwendung

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

Biochem./physiol. Wirkung

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

Leistungsmerkmale und Vorteile

This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H350,H360,H410
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Gefahreneinstufungen: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges