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Merck

D5764

Sigma-Aldrich

2,3-Diphospho-D-glyceric acid pentasodium salt

glycolysis metabolite

Synonym(e):

2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt

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About This Item

Lineare Formel:
C3H3O10P2Na5
CAS-Nummer:
Molekulargewicht:
375.95
MDL-Nummer:
UNSPSC-Code:
12352201
PubChem Substanz-ID:
NACRES:
NA.25

Biologische Quelle

synthetic

Qualitätsniveau

Form

powder

Verunreinigungen

3-phosphoglyceric acid, essentially free

Farbe

white to off-white

Löslichkeit

water: 100 mg/mL, clear, colorless to faintly yellow

Kationenspuren

Na: 24.5-32.5% (anhydrous)

Lagertemp.

−20°C

SMILES String

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

InChIKey

JJEMSNINYKJOBZ-YBBRRFGFSA-N

Anwendung

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Biochem./physiol. Wirkung

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

Manon Bardyn et al.
Metabolites, 10(6) (2020-06-04)
After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study
Chiara Crestani et al.
Journal of veterinary internal medicine, 32(3), 1051-1059 (2018-04-11)
Optimal procedure for storage of feline blood is needed. Open-collection systems have been employed in feline medicine, thus limiting the possibility for storage. To evaluate indicators of quality of feline blood stored for 35 days at +4°C in a closed-collection
Minke A E Rab et al.
American journal of hematology, 94(5), 575-584 (2019-02-21)
In sickle cell disease (SCD), sickle hemoglobin (HbS) polymerizes upon deoxygenation, resulting in sickling of red blood cells (RBCs). These sickled RBCs have strongly reduced deformability, leading to vaso-occlusive crises and chronic hemolytic anemia. To date, there are no reliable
Sitong Zhou et al.
Science advances, 5(5), eaaw4466-eaaw4466 (2019-06-01)
The tight coupling between cerebral blood flow and neural activity is a key feature of normal brain function and forms the basis of functional hyperemia. The mechanisms coupling neural activity to vascular responses, however, remain elusive despite decades of research.
H Gulliksson et al.
Vox sanguinis, 112(1), 33-39 (2016-12-22)
The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation

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