C5424

Conduritol B epoxide

powder, ≥95% (TLC)

• Synonym(e): 1,2-Anhydro-myo-inositol
• CAS-Nummer: 6090-95-5
• MDL-Nummer: MFCD00077326
• UNSPSC-Code: 12352119
• PubChem Substanz-ID: 24892783
• NACRES: NA.32

Eigenschaften

• product name: Conduritol B epoxide,
• Biologische Quelle: synthetic (organic)
• Qualitätsniveau: 100
• Assay: ≥95% (TLC)
• Form: powder
• Löslichkeit: water: 20 mg/mL, clear, colorless to faintly yellow
• Lagertemp.: 2-8°C
• SMILES String: OC1C(O)C(O)C2OC2C1O
• InChI: 1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H
• InChIKey: ZHMWOVGZCINIHW-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Conduritol B epoxide (CBE) is a mix of 1-L-1,2-anhydro-myo-inositol and 1-D-1,2-anhydro-myo-inositol.

Anwendung

Conduritol B epoxide has been used as an inhibitor of GBA1 to discriminate between acid β-glucosidase (GBA1) and non-lysosomal β-glucosidase (GBA2) activity in β-glucosidase activity assay. It has also been used as a selective glucocerebrosidase (GCase) inhibitor.

Biochem./physiol. Wirkung

Conduritol B epoxide (CBE) is capable of inactivating sucrase-isomaltase irreversibly. It can be used to produce cell and animal models to study on Gaucher disease (GD) and Parkinson′s disease (PD).

β-Glucosidase inhibitor

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)