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C1017

Sigma-Aldrich

Citrinin

from Penicillium citrinum, ≥98% (HPLC), powder, mycotoxin

Synonym(e):

4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carbonsäure

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About This Item

Empirische Formel (Hill-System):
C13H14O5
CAS-Nummer:
518-75-2
Molekulargewicht:
250.25
Beilstein:
5282243
EG-Nummer:
208-257-2
MDL-Nummer:
MFCD00006912
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24892302
NACRES:
NA.77

product name

Citrinin, from Penicillium citrinum, ≥98% (HPLC)

Biologische Quelle

Penicillium citrinum

Qualitätsniveau

200

Assay

≥98% (HPLC)

Form

powder

Lagertemp.

2-8°C

SMILES String

C[C@H]1OC=C2C(O)=C(C(O)=O)C(=O)C(C)=C2[C@@H]1C

InChI

1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,15H,1-3H3,(H,16,17)/t5-,7-/m1/s1

InChIKey

CQIUKKVOEOPUDV-IYSWYEEDSA-N

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Allgemeine Beschreibung

Citrinin is a mycotoxin from Penicillium citrinin that comprises a quinone methide component.

Anwendung

Citrinin has been used as:
  • a standard for calibration curve preparation for citrinin quantification Monascus purpureus ATCC 36928
  • an internal standard in thin layer chromatography (TLC) for characterizing the citrinin from Aspergillus and Penicillium strains
  • standard to characterize citrinin for rotten apples TLC

Biochem./physiol. Wirkung

Citrinin is a predominant contaminant in agriculture supplies and food. It exhibits genotoxic, embryotoxic, and teratogenic properties. It is hepatonephrotoxin and a potent mycotoxin in rice grains.

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

M R Bragulat et al.
Letters in applied microbiology, 47(4), 286-289 (2009-02-26)
To assess the ability of fungi isolated from grapes to produce patulin and citrinin. A total of 446 Aspergillus isolates belonging to 20 species and 101 Penicillium isolates were inoculated in Czapek yeast extract agar and yeast extract sucrose agar
Effect of dissolved oxygen concentration on red pigment and citrinin production by Monascus purpureus ATCC 36928
Brazilian Journal of Chemical Engineering, 25, 247-253 (2008)
M L Martins et al.
Food additives and contaminants, 19(6), 568-574 (2002-06-04)
Patulin and citrinin are mycotoxins produced by certain fungi mainly belonging to Penicillium and Aspergillus and may be detected in mouldy fruits and fruit products. The data presented here refer to the simultaneous occurrence of patulin and citrinin in 351
Liliana J G Silva et al.
Foods (Basel, Switzerland), 10(1) (2020-12-31)
Citrinin (CIT) deserves attention due to its known toxic effects in mammalian species and its widespread occurrence in food commodities, often along with ochratoxin A, another nephrotoxic mycotoxin. Human exposure, a key element in assessing risk related to food contaminants
H K Frank
Zeitschrift fur Ernahrungswissenschaft, 31(3), 164-177 (1992-09-01)
Citrinin, a nephrotoxic mycotoxin, has been of growing importance also for the "International Agency for Research on Cancer", ever since its presumable role in the occurrence of Balcan endemic nephropathy (BEN) was discussed at the congress on "Mycotoxins, Endemic Nepthropathy
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