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Merck

B3398

Sigma-Aldrich

Monoklonaler ANTI-Human-IgG2-Antikörper

clone HP-6014, purified from hybridoma cell culture

Synonym(e):

Monoclonal Anti-Human IgG2

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

biotin conjugate

Antikörperform

purified from hybridoma cell culture

Antikörper-Produkttyp

secondary antibodies

Klon

HP-6014, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

human

Methode(n)

direct ELISA: 1:30,000

Isotyp

IgG1

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

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Allgemeine Beschreibung

Monoclonal Anti-Human IgG2 (mouse IgG1 isotype) is derived from the hybridoma (HP-60141 ) produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgG is the most abundant serum immunoglobulins of the immune system. IgG2 is a subtype of IgG. IgG is secreted by B cells and is found in blood and extracellular fluids.

Spezifität

Der Antikörper ist spezifisch für Human-IgG2 und ist mit anderen IgG-Unterklassen nicht reaktiv. Dieser Klon wurde in der IUIS/WHO-Studie als der am vielseitigsten einsetzbare IgG2-spezifische monoklonale Antikörper hervorgehoben.

Anwendung

Monoclonal Anti-Human IgG2−Biotin antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and immunoblot.

Biochem./physiol. Wirkung

IgG provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Low IgG2 levels were found in patients with systemic lupus erythematosus (SLE) and juvenile diabetes melitus.

Physikalische Form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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