A0637

DL-2-Aminoadipinsäure

≥99% (TLC), powder, gliotoxic

• Synonym(e): DL-α-Aminoadipic acid
• Lineare Formel: HO₂C(CH₂)₃CH(NH₂)CO₂H
• CAS-Nummer: 542-32-5
• Molekulargewicht: 161.16
• EG-Nummer: 208-809-2
• MDL-Nummer: MFCD00063119
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 24890441
• NACRES: NA.32

Eigenschaften

• product name: DL-2-Aminoadipinsäure, ≥99%
• Qualitätsniveau: 200
• Assay: ≥99%
• Form: powder
• mp (Schmelzpunkt): 196-198 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: NC(CCCC(O)=O)C(O)=O
• InChI: 1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)
• InChIKey: OYIFNHCXNCRBQI-UHFFFAOYSA-N
• Angaben zum Gen: rat ... Grin2b(24410)

Beschreibung

Anwendung

DL-2-Aminoadipic acid (AAA) has been used as an astrotoxin to kill astrocytes that prevent efficient integration of transplanted cells into the retina. It has also been used as a gliotoxin to study the effect of astrocytic swelling on the tortuosity.

Biochem./physiol. Wirkung

DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable